WHO names 12 bacteria that pose the greatest threat to human health

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Antibiotic resistance could shape c-sections, grafts and chemotherapy too dangerous to perform, alerts World Health Organisation

The World Health Organisation( WHO) has published a index of the 12 bacteria which pose the most serious threat to human health because they are resistant to antibiotics.

Health experts had already been warned that resist to the drugs that are used to fight infections could cause a bigger menace to mankind than cancer.

If antibiotics lose their effectiveness, key medical procedures including organ transplants, cesarean section, joint substitutions and chemotherapy could become too dangerous to perform.

About 700,000 people in the world expire yearly due to drug-resistant infections and, if no action is taken, it has been estimated that such infections will kill 10 m people a year by 2050.

Now, the WHO has come up with a index of antibiotic-resistant priority pathogens 12 families of bacteria that pose the most serious threat to human health.

Medical research charity the Wellcome Trust used to say the index was important to steer research into new antibiotics.

The WHO said the 12 bacteria have built-in abilities to find new ways to defy therapy and can pass along genetic substance that allows other bacteria to become drug-resistant as well.

The list categorises bacteria into critical, high-pitched and medium-sized priority groups, according to the urgency of need for new antibiotics.

The most essential group includes multi-drug resistant bacteria that pose a particular threat in hospitals and nursing homes. The bacteria on this list can cause severe and often lethal infections such as bloodstream infections and pneumonia. Other increasingly drug-resistant bacteria, which are deemed high-pitched and medium-sized priority, cause more common diseases such as gonorrhoea and food poisoning is generated by salmonella.

This list is a new tool to ensure R& D[ research and development] responds to urgent public health needs, replied Dr Marie-Paule Kieny, WHOs assistant director-general for health systems and innovation.

Antibiotic resistance is turn and “were about” fast running out of therapy options. If we leave it to sell armies alone, the new antibiotics we most urgently need are not going to be developed in time.

The WHO indicating that it hoped the index would stimulate the administration has put in place policies designed to incentivise the development of new drugs.

Experts came up with the index by scrutinizing a number of criteria, including the way in which deadly the infections the bacteria cause are and whether new antibiotics to treat them are already in the pipeline.

Some bacteria were not included in the index. The WHO said there was already dedicated programs working on drug-resistant tuberculosis. Other bacteria, including streptococcus A and B and chlamydia, is likewise omitted since they are do not currently pose an important public health menace.

Commenting on the publication of the index, Tim Jinks, heads of state of drug resistant infections at the Wellcome Trust, replied: This priority pathogens index, developed with input from across local communities, is important to steer experiment in the race against drug resistant infection one of the greatest threats to modern health.

Without effective drugs, doctors cannot treat patients. Within a generation, without new antibiotics, deaths per drug resistant infection could reach 10 m a year. Without new medications to treat lethal infection, lifesaving therapies like chemotherapy and organ transplant, and routine procedures like caesareans and hip substitutions will be potentially fatal.

The WHO list

Three bacteria are considered to be of critical priority 😛 TAGEND

Pseudomonas aeruginosa, carbapenem-resistant

Enterobacteriaceae, carbapenem-resistant, ESBL-producing

Acinetobacter baumannii, carbapenem-resistant

Enterococcus faecium, vancomycin-resistant

Staphylococcus aureus, methicillin-resistant, vancomycin-intermediate and resistant

Helicobacter pylori, clarithromycin-resistant

several species of Campylobacter, fluoroquinolone-resistant

Salmonellae, fluoroquinolone-resistant

Neisseria gonorrhoeae, cephalosporin-resistant, fluoroquinolone-resistant